Colonic mucosal and cytobrush sample cytokine mRNA expression in canine inflammatory bowel disease and their correlation with disease activity, endoscopic and histopathologic score
Fig 5
Relative mRNA expression of IL-1β (A), IL-2 (B), IL-12p40 (C), IL-23p19 (D), TNF-α (E) and CCL28 (F) in the colonic mucosa of low and high CCECAI score dogs with inflammatory bowel disease (IBD). Data is presented as median with 25th and 75th quartiles in each box plot. The whiskers indicate the highest and lowest data within 1.5 times the lengths of the quartiles. Statistical significance was defined as p < 0.05. AU: arbitrary units, IBD: inflammatory bowel disease, IL: interleukin, TNF-α: tumor necrosis factor- alpha, CCL28: chemokine (C-C motif) ligand 28.