Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer
Fig 5
Network skeletonization of neural net mapping of GC-MS to canine-positive indicated and canine-negative indicated urine samples.
The network is depicted as a system of excitatory (red) and inhibitory connection weights (blue). Starting from the output node representing a canine-indicated positive (TP) canine diagnosis of prostate cancer, less significant weights are stripped away to reveal critical connections to the most dominant GC-MS peaks contributing to the canine cancer diagnosis. The top figure shows the net with all weights present, while the bottom figure reveals the peak near 13.139 minutes as positively correlated (i.e., red connection) with canine-positive indication of prostate cancer.