Identifying causative mechanisms linking early-life stress to psycho-cardio-metabolic multi-morbidity: The EarlyCause project
Fig 2
Overall methodology of the EarlyCause project, including (A) research platform of harmonised data from existing resources, research protocols and best practices; (B) triangulation approach, which will capitalise on the complementary strengths of epidemiological and genetic methods in humans, experimental animal and cellular models, and in silico data integration pipelines; and (C) expected results such as new biomarkers and clinical knowledge.