Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice
Fig 5
Intra-renal Mø proliferation and TEC apoptosis in CP-N mice.
Representative photos of F4/80-positive Mø infiltration in the tubular interstitium, TUNEL-positive apoptotic cells in TECs, and caspase-3-positive cells in TECs identified by immunostaining among the NC (A, E, and I), CP+V (B, F and J), and CP+anti-IL-34 Ab (C, G, and K) groups of mice. Original magnification, 200×. Quantitative evaluation of the IHC for F4/80 (D), TUNEL (H), and caspase-3 (L) among the study groups. Data are expressed as the mean ± SEM. The Mann-Whitney U test was used for statistical analysis.