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Brain folding shapes the branching pattern of the middle cerebral artery

Fig 5

Development of the Sylvian fissure.

(A) represents an overview of the growth of the human brain in utero from post conceptional week 23 to 37. (B) represents the volumetric growth of the frontal lobe, central core, temporal and parietal lobes respectively. Logistic denotes the type of fit that was used to calculate the error in the figure (C) shows volumetric growth relative to total intracerebral volume at a given point. The insula and the central core grow at a slower rate than any other region and represent the smallest relative volume throughout gestation (ANCOVA controlling for side and gestational age; F(4, 173) = 123.61, p < 0.0001).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0245167.g005