Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression
Fig 5
Downregulation of androgen receptor does not increase αVβ3 or αVβ6 integrin expression.
Immunoblotting analysis of C4-2B and LNCaP cell lysates after AR downregulation by siRNA to AR. (A) Expression levels of αVβ3 integrin in C4-2B and LNCaP cells after AR downregulation. Immunoblotting was performed under reducing conditions. (B) Expression levels of αVβ6 integrin in C4-2B and LNCaP cells after AR downregulation. Immunoblotting was performed under non-reducing conditions. Actin or TSG101 serves as loading controls. NS, non-silencing.