Discovery of beta-lactamase CMY-10 inhibitors for combination therapy against multi-drug resistant Enterobacteriaceae
Fig 2
Apolar (green), hydrogen bonding donor (blue) and acceptor (red) and negatively (orange) charged SILCS FragMaps overlaid on the active site of CMY-10. The crystal binding mode of IMP in the CMY-10-IMP complex is shown. Consistencies between the crystal binding mode of IMP with FragMaps are shown by arrows.