The significance of cytoplasmic antinuclear antibody patterns in autoimmune liver disease
Fig 2
Representative images of the cytoplasmic antinuclear-antibody staining pattern in HEp-2 cells by using the sera of AILD or non-AILD patients.
The reticular pattern shows granular and filamentous staining throughout the cytoplasm, whereas the speckled pattern shows fine speckles distributed throughout the cytoplasm. The reticular (A) and speckled (B) patterns in patients with primary biliary cholangitis, the reticular pattern in a patient with hepatitis B (C), and the speckled pattern in an osteoarthritis patient (D).