Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales
Fig 3
NASH shifts abundance of Bacteroidales and Erysipelotrichales.
A) Relative abundance of specific taxa at baseline or after 12, and 24 weeks of NASH protocol. B) Bacteroidales abundance is reduced in NASH while C) Erysipelotrichales increases dramatically. Fecal samples were sequenced from 3–7 mice per condition, per timepoint. P values are encoded as * = p < 0.05, ** = p < 0.01, and *** = p < 0.001.