Nephrotic syndrome with focal segmental glomerular lesions unclassified by Columbia classification; Pathology and clinical implication
Fig 3
Outcome evaluation among typical variants of FSGS vs. unclassified group and their subgroups.
(A and B) Kaplan-Meier analysis for cumulative probability of complete remission. There were no significant differences between the typical FSGS group and the unclassified group (A). Among the subgroups, TIP and “simple attachment” had the best therapeutic reactivity. CEL and “endothelial damage” showed moderate response to immunosuppressive treatment (B). (C) Kaplan-Meier curve for 30% decline of eGFR. No significant differences were observed in comparison between the typical FSGS group and the unclassified group and comparison among the subgroups (S2 Fig). Abbreviations: FSGS, Focal segmental glomerulosclerosis; CEL, Cellular variant; TIP, Tip variant; NOS, Not otherwise specified; eGFR, Estimated glomerular filtration ratio.