Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia
Fig 2
Change in the pain tolerance thresholds.
Allodynia state was determined according to the changes in the pain tolerance thresholds between interictal and ictal visits on face and hand. If the pain tolerance change was >3°C on both face and hand the patient was categorized as having generalized allodynia. Localized allodynia was defined if >3°C change was observed on face but not hand. If there was no change or if the change was < 3°C on face and hand that was considered no allodynia. In total there were 7 patients who experienced generalized allodynia and 8 who were categorized as having no allodynia with the remaining 4 experiencing localized allodynia.