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The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension

Fig 5

Images of liver sections in the second experiment.

Representative images of liver sections subjected to H&E staining (A, B) [magnification: ×200], EVG staining (C, D) [magnification: ×100], and immunostaining with CD68 antibody (E, F) [magnification: ×100]. Liver sections from SHRs fed HFC diet in the absence (A, C, E) or the presence (B, D, F) of hydralazine. Scale bar, 100 μm. CV, central vein.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0243846.g005