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Systematic review and meta-analysis of late auditory evoked potentials as a candidate biomarker in the assessment of tinnitus

Fig 2

Calculation of the Standardized Mean Difference (SMD) for P300 latency.

Illustration to clarify the used procedure. Raw mean differences and within-study standard deviations were calculated based on the reported mean values and between-subject variations. SMDs were then calculated and used as input for the multivariate model. Grey lines represent control subjects and black lines represent tinnitus patients. Individual subjects are represented by dotted lines while the average response is presented as a solid line.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0243785.g002