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Olfactory response as a marker for Alzheimer’s disease: Evidence from perceptual and frontal lobe oscillation coherence deficit

Fig 4

a) Beta-band component of a sample epoch from the data of the Fz and Cz electrodes for one AD (top) and one healthy (bottom) participant. b) Gamma-band component of a sample epoch from the data of the Fz and Cz electrodes for one AD (top) and one healthy (bottom) participant. c) Top: Regression of beta-band ImCoh value with age. Values for the two groups are shown as histograms. Bottom: Age-adjusted beta-band ImCoh values are shown as histograms for the two groups. d) Top: Regression of gamma-band ImCoh value with age. Values for the two groups are shown as histograms. Bottom: Age-adjusted gamma-band ImCoh values are shown as histograms for the two groups. e) Statistical significance of the gamma-band ImCoh value difference between mild AD patients and healthy participants. The Fz-Cz connection is the most significant connection with p-value < 0.05. f) The ImCoh value of the Fz-Cz connection measured in each frequency band. Statistically significant frequency bands are denoted by + and x marks.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0243535.g004