OpenStats: A robust and scalable software package for reproducible analysis of high-throughput phenotypic data
Fig 3
Schematic view of the IMPC statistical pipeline.
The measurement of several parameters per specimen are collected from 13 centres all over the world, inspected for possible QC issues, carefully filtered to form individual working datasets, pre-optimised for being processed by the cluster computing platform and ultimately passed to the statistical analysis engine either PhenStat or OpenStats for the statistical analysis. The analysis engine is in charge of applying a proper statistical method to each working dataset and stores the analysis results in a format that enhances the downstream processes. All outputs from the statistical engine are inspected for the failures, errors and must pass a random QC check prior to being released to the downstream processes.