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Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression profiles

Fig 2

Mutated genes of interest.

Circos plots showing the distribution, across the human genomes, of the 3700 pre-selected genes (inner circle) commonly mutated BRCA-US, OV-US, and PRAD-US cancer data sets, including COSMIC (orange) and non-COSMIC (green) genes (red); The second circle from the middle shows the 1537 cancer-causing candidate genes, with non-COSMIC genes in blue, and COSMIC genes in red labeled with their gene names.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0242780.g002