Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjögren’s syndrome-associated dry eyes
Fig 5
Mucin-related gene expression levels in the SS-DE and age- and sex-matched control groups at 4 weeks after the initiation of rebamipide instillation treatment.
Mucin-related gene expression levels in the SS-DE at 4 weeks after the initiation of rebamipide treatment were compared with those in age- and sex-matched control groups. MUC5AC mRNA expression levels in the SS-DE group were significantly higher than in the control group. (a) MUC5AC mRNA expression; (b) SPDEF mRNA expression; (c) MUC16 mRNA expression. * p < 0.05, Mann-Whitney U-test. SS-DE, Sjögren’s syndrome-associated dry eyes.