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Effects of dose titration on adherence and treatment duration of pregabalin among patients with neuropathic pain: A MarketScan database study

Fig 1

Flow chart of study sample.

a. Index: first pregabalin claim. b. Neuropathic pain (NeP): diabetic peripheral neuropathy, spinal cord injury, or post-herpetic neuralgia within 12 months prior to or 1 month following the index. c. Non-NeP indications: epilepsy, fibromyalgia, amyotrophic lateral sclerosis, or multiple sclerosis. d. New pregabalin users: no pregabalin use within 12 months prior to the index.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0242467.g001