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Divergent organ-specific isogenic metastatic cell lines identified using multi-omics exhibit differential drug sensitivity

Fig 5

The up- and down-regulated proteomic-based interconnected pathway network maps of unique to the lung-231 cell line.

The size range of the nodes correlates to the size of the protein sets while the range of hues of the nodes correlates with the q-values, which is correlated to the size of the number of observed proteins. The edges represent the overlap of shared proteins between the connected nodes with the width of the edges representative of the size of the overlap and their color denoting the number of the observed proteins that are shared.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0242384.g005