High-dose naloxone: Effects by late administration on pain and hyperalgesia following a human heat injury model. A randomized, double-blind, placebo-controlled, crossover trial with an enriched enrollment design
Fig 5
Sensitizer categorization following cutaneous heat injuries.
Secondary hyperalgesia areas as measured at baseline on Sessions 0, 1, and 3. Red lines illustrate ‘high-sensitizers’ and blue lines illustrate ‘low-sensitizers’. The blue rectangle shows the Q1 interval and the red rectangle shows the Q4 interval as defined on Session 0.