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Functional role of vitronectin in breast cancer

Fig 5

Vitronectin expression is modulated by PI3K/AKT axis.

A. Displays the pseudo blot extracted from SimpleWestern experiments. There are four cell-lines- MDA-MB-231, MCF7, MDA-MB-468, HCC1599, were used to evaluate the signaling cascade relationship. Different protein expression levels were normalized with an averaged house-keeping GAPDH and β-actin expression B. Compares vitronectin concentration levels in four BC cell lines. C. PI3K concentration levels in BC same cell-lines. D. compares AKT concentration and, E. P-AKT concentration levels in the same four BC cell lines.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0242141.g005