Analysis of mutations of defensin protein using accelerated molecular dynamics simulations
Fig 6
The area-per-lipid profiles of every constitutive lipid for each protein-membrane system comprising a wild-type RsAFP2, its two mutants and two homologs.
Increasing area-per-lipid profiles increased membrane deformation. The profile remains very stable for RsAFP2 in comparison to its mutants suggesting that the mutation bring higher deformity in the fungal membranes.