Blood-brain barrier permeability analysis of plant ceramides
Fig 2
In vivo Blood-Brain Barrier (BBB) permeability of C15 ceramide.
(A) Chemical structure of d18:2/C15-ceramide. (B) Levels of d18:2/C15-ceramide in the brain after injection at low and high dosage. Data are presented as means ± SD (Low dosage: n = 3, each group, High dosage: Control, n = 9; d18:2/C15, n = 8; ns, not significant; *p<0.05 by t-test). (C) Levels of d18:2/C15-SM and d18:2/C15-GlcCer in the brain after injection at low and high dosage. Data are presented as means ± SD (Low dosage: n = 3, each group, High dosage: Control, n = 9; d18:2/C15, n = 8; ns, not significant by t-test).