A Tenon’s capsule/bulbar conjunctiva interface biomimetic to model fibrosis and local drug delivery
Fig 5
Macrophages can be successfully incorporated in compressed collagen gels with maintenance of the contraction potential and structure.
A) Contraction kinetics of compressed gels with/without macrophages. Compressed gels with the addition of macrophages maintain a tissue-like contraction pattern. Porcine conjunctiva contraction from Fig 1B was replotted for reference. B) 3D reconstruction of compressed gel with fibroblasts (thin arrow) and macrophages (thick arrow) on day 21. 3D grid: 1 unit = 62.45 μm.