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Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells

Fig 5

Bergenin suppressed cytokine-induced beta cell apoptosis.

Exposure of beta cell to proinflammatory cytokines (IL-1β, INF-γ, and TNF-α) lead to apoptosis. However, the addition of bergenin suppressed deleterious effects of cytokine cocktail and prevented apoptosis in INS-1E cells.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0241349.g005