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Comparative proteomic analysis of silica-induced pulmonary fibrosis in rats based on tandem mass tag (TMT) quantitation technology

Fig 5

Scatter diagram of the enriched KEGG pathways of the 285 DEP.

The top twenty terms are shown. Degree of enrichment was measured by Rich factor, Q value, and the number of genes enriched in one pathway. The Rich factor is the ratio of the number of differentially expressed genes enriched in one pathway and the total annotation number. The greater the Rich factor value, the higher the degree of enrichment. The Q value is a variant of a p value, for which lower numbers equate to significant enrichment. The Y-axis represents the name of the pathway and the X-axis represents the Rich factor. The point size is the number of differentially expressed genes in one pathway, and the color of the point indicates the range of the Q value.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0241310.g005