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Comparative proteomic analysis of silica-induced pulmonary fibrosis in rats based on tandem mass tag (TMT) quantitation technology

Fig 2

DEPs between the control and model groups.

A shows volcano plot of proteins. The threshold set for DEPs was a fold change (FC) ≥1.8 and p value < 0.05. 145 proteins are up-regulated (red) and 140 proteins are down-regulated (green). B shows heat map of DEPs between the control and model groups, with folds > ± 1.8 and p value < 0.05. Each column represents a sample and each row represents a significant protein. [28S21], [28S22] and [28S23] represent model samples; [28C15], [28C16] and [28C17] represent control samples. 285 proteins were found to be significantly differentially expressed.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0241310.g002