LC-MS/MS analysis of lesional and normally looking psoriatic skin reveals significant changes in protein metabolism and RNA processing
Fig 2
Heat map representing three clusters of DEPs involved in mRNA translation, according to the average quantitative expression levels in two groups of samples.
a) Ribosome proteins; b) Aminoacyl-tRNA synthetases; c) Translation initiation elongation and termination factors; From left to right column–the results of comparative analysis for normally looking skin of the patients vs. skin of the healthy volunteers, lesional vs. normally looking skin of the patients, and lesional skin of the patients vs. skin of the healthy volunteers. Red color indicates low expression levels whereas green color indicates high expression levels. The DEPs uniprot ID, official gene symbols of the encoding genes, fold changes and Benjamini corrected P-values are shown in S2 Table in S1 File.