The inclusion of blastomeres into the inner cell mass in early-stage human embryos depends on the sequence of cell cleavages during the fourth division
Fig 3
Example of blastomere distribution to the ICM or TE obtained by tracking the position of refractile bodies.
In these sequential photographs, the refractile bodies were distributed to the ICM (Fig 3) or the TE (Fig 4). The white arrows indicate the large refractile bodies in 2PN zygotes and 2-cell, 4-cell, 8-cell, morula, and blastocyst stage embryos. The numbers indicate the time in hours from ICSI.