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A highly active heparinase I from Bacteroides cellulosilyticus: Cloning, high level expression, and molecular characterization

Fig 2

Effect of induction temperature on the activity (A) and the expression (B) (SDS-PAGE image of the BcHep-I at different temperatures.

M: protein molecular weight marker, lane 1~6: supernatant after the sonication of the IPTG induced E. coli at 15, 20, 25, 30, 35, and 37°C; lane 7~12: precipitate after the sonicated of the IPTG induced E. coli at 15, 20, 25, 30, 35, and 37°C; BcHep-I bands were marked with solid red wireframe) of BcHep-I. Effect of the induction time on the activity of BcHep-I (C). SDS-PAGE of the purified Hep-I (D) (M: protein molecular weight marker, lane 1: the purified BcHep-I).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0240920.g002