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Capillary whole-blood IgG-IgM COVID-19 self-test as a serological screening tool for SARS-CoV-2 infection adapted to the general public

Fig 2

Interpretation of self-test results.

A. The self-test result was interpreted as negative when a Control line (C) was present and readable and the “IgG” and “IgM” lines were absent. It was positive when a “C” and “IgM” (clearly or poorly readable) (case 1), or “C” and “IgG”, or “C”, “IgM” (clearly or poorly readable), and “IgG” lines were present. Finally, it was invalid when the “C” line was absent regardless of the presence or absence of the “IgG” and/or “IgM” line. B. Panel of 8 Exacto® COVID-19 self-test (Biosynex Swiss SA) cassettes, including 4 positive tests (#2, #3, #6 and #7), 2 negative tests (#4 and #8) and 2 invalid tests (#1 and #5). The #2 and #37 are weakly positive for IgM. Each volunteer randomly drew 4 tests among a panel of 8 and interpreted them with the help of the reading and interpretation scale. The observer noted the number of the drawn test and the result given by the participant.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0240779.g002