Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors
Fig 5
T3-induced reduction of mTORC2 and involvement of proteasome pathway in A2780 and HCT116 cells.
(A) Immunoblot analyses were performed using protein lysates from A2780 and HCT116 cells treated with T3 for 16 h at the indicated concentrations. (B) HCT116 cells were pre-treated with T3 for 16 h at the indicated concentrations and then co-treated with 2.5 or 10 μM of MG132 for 6 h. Data are representative of two independent experiments. (A) (B) Uncropped blot images are shown in S2 File.