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Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors

Fig 2

T3-induced reduction of anti-apoptotic proteins expression in A2780 and HCT116 cells.

Immunoblot analyses were performed using protein lysates from A2780 and HCT116 cells treated with T3 for 16 h at the indicated concentrations. The positions of Mcl-1L, Mcl-1S, cFLIPL, and cFLIPS are indicated on the right. Uncropped blot images are shown in S2 File.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0240718.g002