High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis
Fig 11
Differences in myeloid-derived suppressor cells (MDSCs) identified in posthoc analysis among treatment groups.
(A) Dot plots show differences in CD45+ Ly6C+ Ly6G+ CD11b+ SSChigh granulocytic (g) MDSCs among treatment groups. (B) Bar graph depicts mean with standard error bars of the ratio change in gMDSCs as normalized to Sham (percentile of gMDSC treatment group divided by percentile of gMDSC Sham group). (C) Dot plots show differences in CD45+ Ly6G– CD11b+ Ly6C+ SSClow monocytic (m) MDSCs among treatment groups. (D) Bar graph depicts mean with standard error bars of the ratio change in mMDSCs as normalized to Sham (percentile of mMDSC treatment group divided by percentile of mMDSC Sham group). N = 3 (3 independent experiments with 2–3 mice pooled; 8 total mice). *P<0.05, **P<0.01, ****P<0.0001.