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Steady state evoked potential (SSEP) responses in the primary and secondary somatosensory cortices of anesthetized cats: Nonlinearity characterized by harmonic and intermodulation frequencies

Fig 2

Proportion of significant channels (two-way ANOVA) in S1 and S2.

Statistical results from logP and VELogP are identical and shown in black. Results from logSNR are shown in brown. Vertical lines beneath x-axis indicate F1 fundamental and harmonic (red), F2 fundamental (green), and intermodulation frequencies (blue). (A-C) % of channels that were deemed as significant according to two-way ANOVA only for the main effects of the amplitude of F1 (but not F2 main effect nor F1-F2 interaction; A), F2 = 200Hz main effect only (but not F1 main effect nor F1-F2 interaction; B) and both main effects of F1 and F2 as well as F1-F2 interaction (C). We also tried to see a ‘gain control’ type effect by showing logSNR as functions of stimulus amplitudes (S1S3 Figs). Unfortunately, the results were not clear possibly due to 1) variations in experimental conditions (Table 1) and 2) spatial specificity in the neural response (See Figs 35, below).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0240147.g002