Tentative identification of gefitinib metabolites in non-small-cell lung cancer patient plasma using ultra-performance liquid chromatography coupled with triple quadrupole time-of-flight mass spectrometry

Fig 3

MS/MS spectra of sixteen tentative metabolites obtained from their respective precursors under collision-induced dissociation.

The structures were elucidated by analyzing the fragmentation patterns and confirmed using structure matching software MetabolitePilot^™.