Clinical presentation and comorbidities of obstructive sleep apnea-COPD overlap syndrome
Fig 2
Graphic illustration of how OSA and COPD interact to impact on cardiovascular health.
The probability of having hypertension was higher in severe OSA (AHI ≥30) compared to non-severe OSA (AHI <30) and was not impacted by COPD. In moderate-to-severe OSA, COPD was associated with a higher probability of having coronary heart disease, heart failure, particularly peripheral arteriopathy, in a dose-response relationship. COPD did not increase the prevalence of stroke in OSA, irrespective of its severity. Odd ratios are adjusted on age, gender and smoking status. Numerical data are provided in Table 4.