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Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs

Fig 7

Normalised mRNA expression of hepatic regulators of drug transporter and metabolising enzyme regulators MR (A), GR (B), 11βHSD1 (C), 11βHSD2 (D) and PXR (E) between Control (n = 4) and MA (n = 4) groups. MNE, mean normalised expression; MA, methamphetamine; unpaired t-test; *P<0.05 from Control.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0233010.g007