Glucosylceramide synthase maintains influenza virus entry and infection
Fig 4
Glucosylceramide synthase regulates influenza virus reinfection.
Cells were infected with influenza virus as in Fig 2A, and analyzed 18–24 hours later by flow cytometry. (A) HEK 293 UGCG KO cells exhibited an ~40% reduction in influenza virus infection as compared to WT. (B) A549 UGCG KO cells exhibited ~70% reduction in influenza virus infection as compared to WT. (mean ± SE; n = 6). ** p<0.01 using a Mann-Whitney non-parametric test.