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Assessment of acyl-CoA cholesterol acyltransferase (ACAT-1) role in ovarian cancer progression—An in vitro study

Fig 8

Effect of shRNA mediated ACAT-1 inhibition on apoptosis related proteins.

(A) Effect of ACAT-1 inhibition on casapses3/7 activities. Data were expressed as mean ± SD of triplicate experiments. *p < 0.05, compared to scrambled control, Student’s t-test. (B) Western blot analysis of the expression of proteins in the cell lysates. The blots were probed with the respective primary antibodies. β-actin was used as the loading control. All blots were quantified using Odyssey software. (C) Western blot band intensity was quantified by scanning densitometry. Data are means ± SD. *P<0.05, **P<0.01.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0228024.g008