Tissue ACE phenotyping in lung cancer
Fig 5
ACE conformation in normal lung tissues.
Immunoprecipitated ACE activity from 5 homogenates of morphologically normal lung tissues from patients with lung cancer is presented as a normalized value to the pool of 4 homogenates of lung tissue from postmortem lung specimens. This highlights differences in immunoprecipitation pattern of ACE from different homogenates by different antibodies. Data are presented as mean of at least 2–3 independent experiments in duplicates. Bars color-coded—as in Fig 4. Blue boxes-mAbs which binding was changed in all lung cancer tissues in comparison to ACE from “normal” lung tissue.