Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors
Fig 9
Comparative binding mode analysis of proposed inhibitors.
(A) PAK1Tpo423, (B) PAK1, (C) PAK4Sep474 and (D) PAK4. The inhibitors (a-l) are shown in orange, nave blue, chartreuse, orchid, dark red, yellow, dark state gray, aquamarine, coral, golden rod, rosy brown and dark magenta colors, respectively.