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Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors

Fig 6

Comparative ribbon analysis of group-II PAKs on the basis of MD simulation analysis.

Ribbon representation of (A and B) PAK4 and PAK4^Sep474, (C and D) PAK5 and PAK5^Sep602 and (E and F) PAK6 and PAK6^Sep560 structures. Color codes are given in the Fig 3 legend.

doi: https://doi.org/10.1371/journal.pone.0225132.g006