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Urine proteomics study reveals potential biomarkers for the differential diagnosis of cholangiocarcinoma and periductal fibrosis

Fig 5

Immunohistochemical staining of three candidate proteins.

LAMP1, LAMP2 and CDHR2, was performed on cadaveric donor liver tissues (the first column) and human CCA microtissue arrays which demonstrated low and high expression (the second and third column). The red arrows indicate the positive of LAMP1 and LAMP2 expression at the luminal surface (red arrows).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0221024.g005