Analysis of the neurotoxin β-N-methylamino-L-alanine (BMAA) and isomers in surface water by FMOC derivatization liquid chromatography high resolution mass spectrometry
Fig 5
Chromatographic performance of the optimized method.
Extracted chromatograms obtained using the present FMOC derivatization–on-line pre-concentration and desalting–UHPLC-HRMS method, including derivatized BMAA and isomers in (a) method procedural blank, (b) blank surface water matrix, (c) blank surface water matrix spiked at 5 ng L-1 with the targeted analytes, and (d) blank surface water spiked at 200 ng L-1 with the internal standard.