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Satellite glial cells modulate cholinergic transmission between sympathetic neurons

Fig 5

Postnatal development of neurons and satellite glia in the Superior Cervical Ganglion (SCG).

(a-b) Representative confocal images of (a) P2 and (b) P21 SCG. Sympathetic neurons were stained for the neuron-specific marker MAP2 (red), satellite glial cells for the glial cell marker S100β (green) and cell nuclei using DAPI (blue). Scale bar = 100 μm. (c-d) Quantification of (c) neuron soma size, measured as average cell area in the section and (d) neuronal and glial cell densities from sections of P2 (n = 3; mean ± s.e.m.) and 3 wks (n = 3; mean ± s.e.m.). ***p<0.001, **p<0.01, *p<0.05 determined by ANOVA followed by pairwise post hoc (Tukey’s HSD) comparison test.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0218643.g005