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Computational, crystallographic studies, cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues

Fig 2

Molecular structure of compounds ethyl 7-acetyl-3-benzoyl-2-methyl-indolizine-1-carboxylate (3), ethyl 7-acetyl-3-benzoyl-2-ethyl-indolizine-1-carboxylate (4), ethyl 7-acetyl-3-(4-chlorobenzoyl)-2-ethyl-indolizine-1-carboxylate (5), and diethyl 3-(4-fluorobenzoyl)indolizine-1,2-dicarboxylate (6) for their anti-TB activity against MDR strains of MTB [10].

Fig 2

doi: https://doi.org/10.1371/journal.pone.0217270.g002