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Conserved regulation of neurodevelopmental processes and behavior by FoxP in Drosophila

Fig 5

MB α-lobe morphology is affected in FoxP-/- flies.

(A-B) Maximum projection of MB image stacks of fly brains stained with anti-Fasll. Scale bar corresponds to 20 μm. (A) Wildtype and (B) FoxP mutants (FoxP-/-), arrowheads indicate MB α-lobes. (C) MB α-lobes area. Maximum projection of MB Kenyon cells, (D) Wildtype flies co-immunostained with anti-FoxP (magenta) and anti-Dac (green), (E) w;;GFP-FoxP co-immunostained with anti-GFP (green) and anti-Dac (magenta). Scale bar corresponds to 20 µm. Data are represented as average and SEM of a minimum of 31 α-lobes. T-test between conditions was performed to determine significance (***, p<0.001). Images were obtained from male brains at 0–2 hours post-eclosion. For the underlying numerical data see S8 Table.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0211652.g005