Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions
Fig 7
Generation of PSMA amplicons from non-cHSA tumor histology.
Immunohistochemical evaluation of tumor from Dog 4, showing immunopositivity for vimentin, neuron-specific enolase, and PSMA only. Dotted black line separates normal liver tissue (right) from tumor tissue (left). CD18 and CD31 immunohistochemistry fail to demonstrate immunoreactivity within tumor cells, but do stain resident macrophages and normal blood vessels, respectively. Magnification 400x; abbreviations CK, cytokeratin; VM, vimentin; NSE, neuron-specific enolase.