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Innate and acquired tolerance to bitter stimuli in mice

Fig 5

Two-bottle preference ratios for concentration series of DB (n = 8), QHCl (n = 7), CAF (n = 8), SAL (n = 8), and EGCG (n = 8) measured after a 3-week period of exposure to the same bitter compound (open circles) superimposed on those measured without the exposure period (closed circles).

# and * indicate the lowest concentrations at which preference ratios fell significantly (p < 0.05) below indifference (0.5) before and after the long bitter exposure, respectively. Solid and dashed lines represent curves fit to the average ratios for the NE and E groups, respectively. Gray lines represent the indifference level (0.5).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0210032.g005